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Genome-wide analysis of chromatin features identifies histone modification sensitive and insensitive yeast transcription factors

We propose a method to predict yeast transcription factor targets by integrating histone modification profiles with transcription factor binding motif information. It shows improved predictive power compared to a binding motif-only method. We find that transcription factors cluster into histone-sens...

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Detalles Bibliográficos
Autores principales: Cheng, Chao, Shou, Chong, Yip, Kevin Y, Gerstein, Mark B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334597/
https://www.ncbi.nlm.nih.gov/pubmed/22060676
http://dx.doi.org/10.1186/gb-2011-12-11-r111