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Discovery of active enhancers through bidirectional expression of short transcripts

BACKGROUND: Long-range regulatory elements, such as enhancers, exert substantial control over tissue-specific gene expression patterns. Genome-wide discovery of functional enhancers in different cell types is important for our understanding of genome function as well as human disease etiology. RESUL...

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Detalles Bibliográficos
Autores principales: Melgar, Michael F, Collins, Francis S, Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334599/
https://www.ncbi.nlm.nih.gov/pubmed/22082242
http://dx.doi.org/10.1186/gb-2011-12-11-r113