Interrogation of global mutagenesis data with a genome scale model of Neisseria meningitidis to assess gene fitness in vitro and in sera

BACKGROUND: Neisseria meningitidis is an important human commensal and pathogen that causes several thousand deaths each year, mostly in young children. How the pathogen replicates and causes disease in the host is largely unknown, particularly the role of metabolism in colonization and disease. Com...

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Detalles Bibliográficos
Autores principales: Mendum, Tom A, Newcombe, Jane, Mannan, Ahmad A, Kierzek, Andrzej M, McFadden, Johnjoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334622/
https://www.ncbi.nlm.nih.gov/pubmed/22208880
http://dx.doi.org/10.1186/gb-2011-12-12-r127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334622/
https://www.ncbi.nlm.nih.gov/pubmed/22208880
http://dx.doi.org/10.1186/gb-2011-12-12-r127

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