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Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration

INTRODUCTION: Interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) are up-regulated in injured and osteoarthritic knee joints. IL-1 and TNF-α inhibit integrative meniscal repair; however, the mechanisms by which this inhibition occurs are not fully understood. Transforming growth factor-β1 (TGF-...

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Detalles Bibliográficos
Autores principales: Riera, Katherine M, Rothfusz, Nicole E, Wilusz, Rebecca E, Weinberg, JB, Guilak, Farshid, L McNulty, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334636/
https://www.ncbi.nlm.nih.gov/pubmed/22087734
http://dx.doi.org/10.1186/ar3515