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Matrix metalloproteinase-3 inhibitor retards treadmill running-induced cartilage degradation in rats

INTRODUCTION: The effect of intra-articular injection of matrix metalloproteinase (MMP)-3 inhibitor was investigated in a rat model to understand the role of MMP-3 in cartilage degradation induced by excessive loading from running. METHODS: A total of 24 male Wistar rats were randomly assigned into...

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Detalles Bibliográficos
Autores principales: Ni, Guo-Xin, Zhan, Li-Qiong, Gao, Mei-Qin, Lei, Lei, Zhou, Yue-Zhu, Pan, Yan-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334642/
https://www.ncbi.nlm.nih.gov/pubmed/22114772
http://dx.doi.org/10.1186/ar3521