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Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis

INTRODUCTION: Articular cartilage functions in withstanding mechanical loads and provides a lubricating surface for frictionless movement of joints. Osteoarthritis, characterised by cartilage degeneration, develops due to the progressive erosion of structural integrity and eventual loss of functiona...

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Detalles Bibliográficos
Autores principales: Thomas, Rhian S, Clarke, Alan R, Duance, Victor C, Blain, Emma J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334656/
https://www.ncbi.nlm.nih.gov/pubmed/22151902
http://dx.doi.org/10.1186/ar3536