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Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects

INTRODUCTION: Rheumatoid arthritis (RA) is considered a T cell driven autoimmune disease, therefore, the ability of B cell depleting biologics, e.g., anti-CD20 antibodies, to alleviate RA is unclear. This study examined the proportions of IL-17-secreting lymphocytes in the blood of healthy subjects...

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Detalles Bibliográficos
Autores principales: Eggleton, Paul, Bremer, Edwin, Tarr, Joanna M, de Bruyn, Marco, Helfrich, Wijnand, Kendall, Alexandra, Haigh, Richard C, Viner, Nick J, Winyard, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334661/
https://www.ncbi.nlm.nih.gov/pubmed/22171710
http://dx.doi.org/10.1186/ar3541