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Isoalantolactone Induces Reactive Oxygen Species Mediated Apoptosis in Pancreatic Carcinoma PANC-1 Cells

Isoalantolactone, a sesquiterpene lactone compound possesses antifungal, antibacteria, antihelminthic and antiproliferative activities. In the present study, we found that isoalantolactone inhibits growth and induces apoptosis in pancreatic cancer cells. Further mechanistic studies revealed that ind...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad, Ding, Chuan, Rasul, Azhar, Yi, Fei, Li, Ting, Gao, Hongwen, Gao, Rong, Zhong, Lili, Zhang, Kun, Fang, Xuedong, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334669/
https://www.ncbi.nlm.nih.gov/pubmed/22532787
http://dx.doi.org/10.7150/ijbs.3753