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Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart

BACKGROUND: Cardiovascular toxicity is a major limiting factor in drug development and requires multiple cost-effective models to perform toxicological evaluation. Zebrafish is an excellent model for many developmental, toxicological and regenerative studies. Using approaches like morpholino knockdo...

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Detalles Bibliográficos
Autores principales: Kitambi, Satish Srinivas, Nilsson, Erik S, Sekyrova, Petra, Ibarra, Cristian, Tekeoh, Gilbert Nyah, Andäng, Michael, Ernfors, Patrik, Uhlén, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334682/
https://www.ncbi.nlm.nih.gov/pubmed/22449203
http://dx.doi.org/10.1186/1472-6793-12-3