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Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways

Neurodegeneration, induced by misfolded tau protein, and neuroinflammation, driven by glial cells, represent the salient features of Alzheimer's disease (AD) and related human tauopathies. While tau neurodegeneration significantly correlates with disease progression, brain inflammation seems to...

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Detalles Bibliográficos
Autores principales: Zilka, Norbert, Kazmerova, Zuzana, Jadhav, Santosh, Neradil, Peter, Madari, Aladar, Obetkova, Dominika, Bugos, Ondrej, Novak, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334709/
https://www.ncbi.nlm.nih.gov/pubmed/22397366
http://dx.doi.org/10.1186/1742-2094-9-47