Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

BACKGROUND: The epidermal growth factor receptor (EGFR) is a validated therapeutic target in non-small cell lung cancer (NSCLC). However, current single agent receptor targeting does not achieve a maximal therapeutic effect, and some mutations confer resistance to current available agents. In the cu...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Kronenberger, Peter, Teugels, Erik, Umelo, Ijeoma Adaku, De Grève, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334713/
https://www.ncbi.nlm.nih.gov/pubmed/22436374
http://dx.doi.org/10.1186/1741-7015-10-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334713/
https://www.ncbi.nlm.nih.gov/pubmed/22436374
http://dx.doi.org/10.1186/1741-7015-10-28

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