Cargando…

Microparticles as biological vectors of activated protein C treatment in sepsis

Activated protein C (APC), a physiological coagulation inhibitor, has been shown to reduce mortality in patients with severe sepsis. APC exerts pleiotropic cytoprotection by a mechanism that requires its interaction with endothelial cell protein C receptor and protease-activated receptor-1 on target...

Descripción completa

Detalles Bibliográficos
Autor principal: Andriantsitohaina, Ramaroson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334738/
https://www.ncbi.nlm.nih.gov/pubmed/22017971
http://dx.doi.org/10.1186/cc10416