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Microparticles as biological vectors of activated protein C treatment in sepsis

Activated protein C (APC), a physiological coagulation inhibitor, has been shown to reduce mortality in patients with severe sepsis. APC exerts pleiotropic cytoprotection by a mechanism that requires its interaction with endothelial cell protein C receptor and protease-activated receptor-1 on target...

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Detalles Bibliográficos
Autor principal:	Andriantsitohaina, Ramaroson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334738/ https://www.ncbi.nlm.nih.gov/pubmed/22017971 http://dx.doi.org/10.1186/cc10416

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