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Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients

INTRODUCTION: Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook the pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD...

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Detalles Bibliográficos
Autores principales: Heming, Nicholas, Faisy, Christophe, Urien, Saïk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334757/
https://www.ncbi.nlm.nih.gov/pubmed/21917139
http://dx.doi.org/10.1186/cc10448