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IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis

INTRODUCTION: Interleukin 17A (IL17A) plays a key role in host defense against microbial infection including Gram-positive bacteria. Genetic factors contribute to the host defense, but the role of IL17A single nucleotide polymorphisms (SNPs) has not yet been investigated in severe sepsis. Therefore,...

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Detalles Bibliográficos
Autores principales: Nakada, Taka-aki, Russell, James A, Boyd, John H, Walley, Keith R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334805/
https://www.ncbi.nlm.nih.gov/pubmed/22026963
http://dx.doi.org/10.1186/cc10515