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Trypanosomal histone γH2A and the DNA damage response

DNA damage and repair in trypanosomatids impacts virulence, drug resistance and antigenic variation but, currently, little is known about DNA damage responses or cell cycle checkpoints in these divergent protozoa. One of the earliest markers of DNA damage in eukaryotes is γH2A(X), a serine phosphory...

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Detalles Bibliográficos
Autores principales: Glover, Lucy, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334830/
https://www.ncbi.nlm.nih.gov/pubmed/22353557
http://dx.doi.org/10.1016/j.molbiopara.2012.01.008