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TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse

Transient receptor potential ankyrin 1 (TRPA1) is an ion channel involved in thermosensation and nociception. TRPA1 is activated by exogenous irritants and also by oxidants formed in inflammatory reactions. However, our understanding of its role in inflammation is limited. Here, we tested the hypoth...

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Detalles Bibliográficos
Autores principales: Moilanen, Lauri J., Laavola, Mirka, Kukkonen, Meiju, Korhonen, Riku, Leppänen, Tiina, Högestätt, Edward D., Zygmunt, Peter M., Nieminen, Riina M., Moilanen, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334855/
https://www.ncbi.nlm.nih.gov/pubmed/22532928
http://dx.doi.org/10.1038/srep00380