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TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse
Transient receptor potential ankyrin 1 (TRPA1) is an ion channel involved in thermosensation and nociception. TRPA1 is activated by exogenous irritants and also by oxidants formed in inflammatory reactions. However, our understanding of its role in inflammation is limited. Here, we tested the hypoth...
Autores principales: | Moilanen, Lauri J., Laavola, Mirka, Kukkonen, Meiju, Korhonen, Riku, Leppänen, Tiina, Högestätt, Edward D., Zygmunt, Peter M., Nieminen, Riina M., Moilanen, Eeva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334855/ https://www.ncbi.nlm.nih.gov/pubmed/22532928 http://dx.doi.org/10.1038/srep00380 |
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