Phocid Seal Leptin: Tertiary Structure and Hydrophobic Receptor Binding Site Preservation during Distinct Leptin Gene Evolution

The cytokine hormone leptin is a key signalling molecule in many pathways that control physiological functions. Although leptin demonstrates structural conservation in mammals, there is evidence of positive selection in primates, lagomorphs and chiropterans. We previously reported that the leptin ge...

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Detalles Bibliográficos
Autores principales: Hammond, John A., Hauton, Chris, Bennett, Kimberley A., Hall, Ailsa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334926/
https://www.ncbi.nlm.nih.gov/pubmed/22536379
http://dx.doi.org/10.1371/journal.pone.0035395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334926/
https://www.ncbi.nlm.nih.gov/pubmed/22536379
http://dx.doi.org/10.1371/journal.pone.0035395

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