High-Order SNP Combinations Associated with Complex Diseases: Efficient Discovery, Statistical Power and Functional Interactions

There has been increased interest in discovering combinations of single-nucleotide polymorphisms (SNPs) that are strongly associated with a phenotype even if each SNP has little individual effect. Efficient approaches have been proposed for searching two-locus combinations from genome-wide datasets....

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Detalles Bibliográficos
Autores principales: Fang, Gang, Haznadar, Majda, Wang, Wen, Yu, Haoyu, Steinbach, Michael, Church, Timothy R., Oetting, William S., Van Ness, Brian, Kumar, Vipin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334940/
https://www.ncbi.nlm.nih.gov/pubmed/22536319
http://dx.doi.org/10.1371/journal.pone.0033531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334940/
https://www.ncbi.nlm.nih.gov/pubmed/22536319
http://dx.doi.org/10.1371/journal.pone.0033531

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