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Kinetics of PKCε Activating and Inhibiting Llama Single Chain Antibodies and Their Effect on PKCε Translocation in HeLa Cells

Dysregulation of PKCε is involved in several serious diseases such as cancer, type II diabetes and Alzheimer's disease. Therefore, specific activators and inhibitors of PKCε hold promise as future therapeutics, in addition to being useful in research into PKCε regulated pathways. We have previo...

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Detalles Bibliográficos
Autores principales: Summanen, Milla, Granqvist, Niko, Tuominen, Raimo K., Yliperttula, Marjo, Verrips, C. Theo, Boonstra, Johannes, Blanchetot, Christophe, Ekokoski, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334965/
https://www.ncbi.nlm.nih.gov/pubmed/22536418
http://dx.doi.org/10.1371/journal.pone.0035630