Cargando…
Kinetics of PKCε Activating and Inhibiting Llama Single Chain Antibodies and Their Effect on PKCε Translocation in HeLa Cells
Dysregulation of PKCε is involved in several serious diseases such as cancer, type II diabetes and Alzheimer's disease. Therefore, specific activators and inhibitors of PKCε hold promise as future therapeutics, in addition to being useful in research into PKCε regulated pathways. We have previo...
Autores principales: | Summanen, Milla, Granqvist, Niko, Tuominen, Raimo K., Yliperttula, Marjo, Verrips, C. Theo, Boonstra, Johannes, Blanchetot, Christophe, Ekokoski, Elina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334965/ https://www.ncbi.nlm.nih.gov/pubmed/22536418 http://dx.doi.org/10.1371/journal.pone.0035630 |
Ejemplares similares
-
Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008) -
PKCε phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration
por: Kumar, Varun, et al.
Publicado: (2018) -
Impact of PKCε downregulation on autophagy in glioblastoma cells
por: Toton, Ewa, et al.
Publicado: (2018) -
Tissue-specific conditional PKCε knockout mice: a model to precisely reveal PKCε functional role in initiation, promotion and progression of cancer
por: Hafeez, Bilal Bin, et al.
Publicado: (2016) -
PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer’s Disease Hippocampus
por: Millien, Guetchyn, et al.
Publicado: (2022)