MicroRNA Genes and Their Target 3′-Untranslated Regions Are Infrequently Somatically Mutated in Ovarian Cancers

MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer. MiRNA function is most often achieved through binding to the 3′-untranslated region of the target protein coding gene. Mutation screening...

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Detalles Bibliográficos
Autores principales: Ryland, Georgina L., Bearfoot, Jennifer L., Doyle, Maria A., Boyle, Samantha E., Choong, David Y. H., Rowley, Simone M., Tothill, Richard W., Gorringe, Kylie L., Campbell, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334977/
https://www.ncbi.nlm.nih.gov/pubmed/22536442
http://dx.doi.org/10.1371/journal.pone.0035805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334977/
https://www.ncbi.nlm.nih.gov/pubmed/22536442
http://dx.doi.org/10.1371/journal.pone.0035805

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