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Tau Phosphorylation and μ-Calpain Activation Mediate the Dexamethasone-Induced Inhibition on the Insulin-Stimulated Akt Phosphorylation

Evidence has suggested that insulin resistance (IR) or high levels of glucocorticoids (GCs) may be linked with the pathogenesis and/or progression of Alzheimer's disease (AD). Although studies have shown that a high level of GCs results in IR, little is known about the molecular details that li...

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Detalles Bibliográficos
Autores principales: Liu, Yudong, Su, Ying, Sun, Shenggang, Wang, Tao, Qiao, Xian, Run, Xiaoqin, Liang, Zhihou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335002/
https://www.ncbi.nlm.nih.gov/pubmed/22536436
http://dx.doi.org/10.1371/journal.pone.0035783