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Prion Protein Is a Key Determinant of Alcohol Sensitivity through the Modulation of N-Methyl-D-Aspartate Receptor (NMDAR) Activity

The prion protein (PrP) is absolutely required for the development of prion diseases; nevertheless, its physiological functions in the central nervous system remain elusive. Using a combination of behavioral, electrophysiological and biochemical approaches in transgenic mouse models, we provide stro...

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Detalles Bibliográficos
Autores principales: Petit-Paitel, Agnès, Ménard, Baptiste, Guyon, Alice, Béringue, Vincent, Nahon, Jean-Louis, Zsürger, Nicole, Chabry, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335038/
https://www.ncbi.nlm.nih.gov/pubmed/22536327
http://dx.doi.org/10.1371/journal.pone.0034691