Cargando…

Optimal Estimation of Ion-Channel Kinetics from Macroscopic Currents

Markov modeling provides an effective approach for modeling ion channel kinetics. There are several search algorithms for global fitting of macroscopic or single-channel currents across different experimental conditions. Here we present a particle swarm optimization(PSO)-based approach which, when u...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wei, Xiao, Feng, Zeng, Xuhui, Yao, Jing, Yuchi, Ming, Ding, Jiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335051/
https://www.ncbi.nlm.nih.gov/pubmed/22536358
http://dx.doi.org/10.1371/journal.pone.0035208