Cargando…
Optimal Estimation of Ion-Channel Kinetics from Macroscopic Currents
Markov modeling provides an effective approach for modeling ion channel kinetics. There are several search algorithms for global fitting of macroscopic or single-channel currents across different experimental conditions. Here we present a particle swarm optimization(PSO)-based approach which, when u...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335051/ https://www.ncbi.nlm.nih.gov/pubmed/22536358 http://dx.doi.org/10.1371/journal.pone.0035208 |