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Characterizing Mutational Heterogeneity in a Glioblastoma Patient with Double Recurrence

Human cancers are driven by the acquisition of somatic mutations. Separating the driving mutations from those that are random consequences of general genomic instability remains a challenge. New sequencing technology makes it possible to detect mutations that are present in only a minority of cells...

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Detalles Bibliográficos
Autores principales: Nickel, Gabrielle C., Barnholtz-Sloan, Jill, Gould, Meetha P., McMahon, Sarah, Cohen, Andrea, Adams, Mark D., Guda, Kishore, Cohen, Mark, Sloan, Andrew E., LaFramboise, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335059/
https://www.ncbi.nlm.nih.gov/pubmed/22536362
http://dx.doi.org/10.1371/journal.pone.0035262