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Characterizing Mutational Heterogeneity in a Glioblastoma Patient with Double Recurrence
Human cancers are driven by the acquisition of somatic mutations. Separating the driving mutations from those that are random consequences of general genomic instability remains a challenge. New sequencing technology makes it possible to detect mutations that are present in only a minority of cells...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335059/ https://www.ncbi.nlm.nih.gov/pubmed/22536362 http://dx.doi.org/10.1371/journal.pone.0035262 |