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Structure of Metaphase Chromosomes: A Role for Effects of Macromolecular Crowding
In metaphase chromosomes, chromatin is compacted to a concentration of several hundred mg/ml by mechanisms which remain elusive. Effects mediated by the ionic environment are considered most frequently because mono- and di-valent cations cause polynucleosome chains to form compact ∼30-nm diameter fi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335069/ https://www.ncbi.nlm.nih.gov/pubmed/22540018 http://dx.doi.org/10.1371/journal.pone.0036045 |