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Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study
High total plasma homocysteine (tHcy) has been associated with cognitive impairment in later life, but it is unclear if this association is causal or is due to confounding. The C677T polymorphism of the 5,10 methylenetetrahydrofolate reductase gene (MTHFR) increases basal tHcy, but its contribution...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335075/ https://www.ncbi.nlm.nih.gov/pubmed/21358708 http://dx.doi.org/10.1038/mp.2011.18 |