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Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study

The Metabochip is a custom genotyping array designed for replication and fine mapping of metabolic, cardiovascular, and anthropometric trait loci and includes low frequency variation content identified from the 1000 Genomes Project. It has 196,725 SNPs concentrated in 257 genomic regions. We evaluat...

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Detalles Bibliográficos
Autores principales: Buyske, Steven, Wu, Ying, Carty, Cara L., Cheng, Iona, Assimes, Themistocles L., Dumitrescu, Logan, Hindorff, Lucia A., Mitchell, Sabrina, Ambite, Jose Luis, Boerwinkle, Eric, Buzkova, Petra, Carlson, Chris S., Cochran, Barbara, Duggan, David, Eaton, Charles B., Fesinmeyer, Megan D., Franceschini, Nora, Haessler, Jeffrey, Jenny, Nancy, Kang, Hyun Min, Kooperberg, Charles, Lin, Yi, Le Marchand, Loic, Matise, Tara C., Robinson, Jennifer G., Rodriguez, Carlos, Schumacher, Fredrick R., Voight, Benjamin F., Young, Alicia, Manolio, Teri A., Mohlke, Karen L., Haiman, Christopher A., Peters, Ulrike, Crawford, Dana C., North, Kari E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335090/
https://www.ncbi.nlm.nih.gov/pubmed/22539988
http://dx.doi.org/10.1371/journal.pone.0035651