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Effect of Central Nervous System Metastases on Treatment Discontinuation and Survival in Older Women Receiving Trastuzumab for Metastatic Breast Cancer

Background. Trastuzumab improves survival in HER2-positive women with metastatic breast cancer (MBC). The consequences of longer survival include a higher likelihood of additional metastases, including those in the central nervous system (CNS). The effect of CNS metastases on both trastuzumab discon...

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Detalles Bibliográficos
Autores principales: Danese, Mark D., Lindquist, Karla, Doan, Justin, Lalla, Deepa, Brammer, Melissa, Griffiths, Robert I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335251/
https://www.ncbi.nlm.nih.gov/pubmed/22570657
http://dx.doi.org/10.1155/2012/819210