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Overexpression of S6 Kinase 1 in Brain Tumours Is Associated with Induction of Hypoxia-Responsive Genes and Predicts Patients' Survival
mTOR/S6K pathway is a crucial regulator of cell growth and metabolism. Deregulated signalling via S6K has been linked to various human pathologies, including metabolic disorders and cancer. Many of the molecules signalling upstream of S6K have been shown to be either mutated or overexpressed in tumo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Journal of Oncology
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335255/ https://www.ncbi.nlm.nih.gov/pubmed/22570651 http://dx.doi.org/10.1155/2012/416927 |