High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis

Moxifloxacin is a broad-spectrum antibacterial 8-methoxy-fluoroquinolone. In order to evaluate the pharmacokinetic properties of moxifloxacin in mouse plasma and brain tissue, we developed a high-performance liquid chromatography (HPLC) method. This study was based on single-drug delivery, intraveno...

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Detalles Bibliográficos
Autores principales: Respaud, Renaud, Grayo, Solene, Singlas, Eric, Dubouch, Sophie, Le Monnier, Alban, Lott, Marie-Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335337/
https://www.ncbi.nlm.nih.gov/pubmed/22567560
http://dx.doi.org/10.1155/2012/436349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335337/
https://www.ncbi.nlm.nih.gov/pubmed/22567560
http://dx.doi.org/10.1155/2012/436349

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