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High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis

Moxifloxacin is a broad-spectrum antibacterial 8-methoxy-fluoroquinolone. In order to evaluate the pharmacokinetic properties of moxifloxacin in mouse plasma and brain tissue, we developed a high-performance liquid chromatography (HPLC) method. This study was based on single-drug delivery, intraveno...

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Detalles Bibliográficos
Autores principales:	Respaud, Renaud, Grayo, Solene, Singlas, Eric, Dubouch, Sophie, Le Monnier, Alban, Lott, Marie-Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335337/ https://www.ncbi.nlm.nih.gov/pubmed/22567560 http://dx.doi.org/10.1155/2012/436349

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