Comparative Study of Cyanobacterial and E. coli RNA Polymerases: Misincorporation, Abortive Transcription, and Dependence on Divalent Cations

If Mg(2+) ion is replaced by Mn(2+) ion, RNA polymerase tends to misincorporate noncognate nucleotide, which is thought to be one of the reasons for the toxicity of Mn(2+) ion. Therefore, most cells have Mn(2+) ion at low intracellular concentrations, but cyanobacteria need the ion at a millimolar c...

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Detalles Bibliográficos
Autores principales: Imashimizu, Masahiko, Tanaka, Kan, Shimamoto, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335489/
https://www.ncbi.nlm.nih.gov/pubmed/22567357
http://dx.doi.org/10.4061/2011/572689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335489/
https://www.ncbi.nlm.nih.gov/pubmed/22567357
http://dx.doi.org/10.4061/2011/572689

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