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Comparative Study of Cyanobacterial and E. coli RNA Polymerases: Misincorporation, Abortive Transcription, and Dependence on Divalent Cations
If Mg(2+) ion is replaced by Mn(2+) ion, RNA polymerase tends to misincorporate noncognate nucleotide, which is thought to be one of the reasons for the toxicity of Mn(2+) ion. Therefore, most cells have Mn(2+) ion at low intracellular concentrations, but cyanobacteria need the ion at a millimolar c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335489/ https://www.ncbi.nlm.nih.gov/pubmed/22567357 http://dx.doi.org/10.4061/2011/572689 |