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Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina

PURPOSE: To examine the potential of NIH-maintained human embryonic stem cell (hESC) lines TE03 and UC06 to differentiate into retinal progenitor cells (hESC-RPCs) using the noggin/Dkk-1/IGF-1/FGF9 protocol. An additional goal is to examine the in vivo dynamics of maturation and retinal integration...

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Detalles Bibliográficos
Autores principales: Hambright, Dustin, Park, Kye-Yoon, Brooks, Matthew, McKay, Ron, Swaroop, Anand, Nasonkin, Igor O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335781/
https://www.ncbi.nlm.nih.gov/pubmed/22539871