Cargando…

Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina

PURPOSE: To examine the potential of NIH-maintained human embryonic stem cell (hESC) lines TE03 and UC06 to differentiate into retinal progenitor cells (hESC-RPCs) using the noggin/Dkk-1/IGF-1/FGF9 protocol. An additional goal is to examine the in vivo dynamics of maturation and retinal integration...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hambright, Dustin, Park, Kye-Yoon, Brooks, Matthew, McKay, Ron, Swaroop, Anand, Nasonkin, Igor O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335781/ https://www.ncbi.nlm.nih.gov/pubmed/22539871

Ejemplares similares

Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines
por: Kaewkhaw, Rossukon, et al.
Publicado: (2016)

Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye
por: Singh, Ratnesh K., et al.
Publicado: (2019)

Retinal Cell Transplantation, Biomaterials, and In Vitro Models for Developing Next-generation Therapies of Age-related Macular Degeneration
por: Rizzolo, Lawrence J, et al.
Publicado: (2022)

Immunohistochemical Detection of 5-Methylcytosine and 5-Hydroxymethylcytosine in Developing and Postmitotic Mouse Retina
por: Singh, Ratnesh K., et al.
Publicado: (2018)

Transcriptome analysis of the retina
por: Swaroop, Anand, et al.
Publicado: (2002)

Expression of deubiquitinating enzyme genes in the developing mammal retina
por: Esquerdo-Barragán, Mariona, et al.
Publicado: (2019)

Limitations and Promise of Retinal Tissue From Human Pluripotent Stem Cells for Developing Therapies of Blindness
por: Singh, Ratnesh K., et al.
Publicado: (2020)

Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery
por: Aryal, Sandeep, et al.
Publicado: (2023)

Transplanted embryonic retinal stem cells have the potential to repair the injured retina in mice
por: Feng, Xia, et al.
Publicado: (2021)

Trilogy Development of Proopiomelanocortin Neurons From Embryonic to Adult Stages in the Mice Retina
por: Zhang, Xuhong, et al.
Publicado: (2021)

PEDF and GDNF are key regulators of photoreceptor development and retinal neurogenesis in reaggregates from chick embryonic retina
por: Volpert, Katja N., et al.
Publicado: (2009)

Pluripotent Stem Cells for Retinal Tissue Engineering: Current Status and Future Prospects
por: Singh, Ratnesh, et al.
Publicado: (2018)

Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina
por: Baleriola, Jimena, et al.
Publicado: (2016)

Ligatin from embryonic chick neural retina
Publicado: (1979)

Lithium Affects Histogenesis of Embryonic Chick Retina
por: Ramchandran, H., et al.
Publicado: (2012)

Ciliary Neurotrophic Factor Induces Genes Associated with Inflammation and Gliosis in the Retina: A Gene Profiling Study of Flow-Sorted, Müller Cells
por: Xue, Wei, et al.
Publicado: (2011)

Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats
por: Thomas, Biju B., et al.
Publicado: (2021)

Next-generation sequencing facilitates quantitative analysis of wild-type and Nrl(−/−) retinal transcriptomes
por: Brooks, Matthew J., et al.
Publicado: (2011)

Retinal Oxygenation in Inherited Diseases of the Retina
por: Türksever, Cengiz, et al.
Publicado: (2021)

ATP and Adenosine in the Retina and Retinal Diseases
por: Ye, Shan-Shan, et al.
Publicado: (2021)

Neuronal Death in the Contralateral Un-Injured Retina after Unilateral Axotomy: Role of Microglial Cells
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2019)

Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells
por: Skytt, D. M., et al.
Publicado: (2016)

Variability in Retinal Neuron Populations and Associated Variations in Mass Transport Systems of the Retina in Health and Aging
por: Zouache, Moussa A.
Publicado: (2022)

Retina-to-Retina Transplantation of Embryonic Donor Cells, Labelled with BrdU or Carrying a Genetic Marker
por: Aramant, Robert, et al.
Publicado: (1992)

Pluripotent stem cell‐derived retinal organoids for disease modeling and development of therapies
por: Kruczek, Kamil, et al.
Publicado: (2020)

Transcriptome Dynamics of Developing Photoreceptors in Three‐Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
por: Kaewkhaw, Rossukon, et al.
Publicado: (2015)

Mouse Embryonic Retina Delivers Information Controlling Cortical Neurogenesis
por: Bonetti, Ciro, et al.
Publicado: (2010)

Not all Notch pathway mutations are equal in the embryonic mouse retina
por: Bosze, Bernadett, et al.
Publicado: (2023)

Genetic architecture of retinal and macular degenerative diseases: the promise and challenges of next-generation sequencing
por: Ratnapriya, Rinki, et al.
Publicado: (2013)

Thicknesses of the retina and choroid in children with retinitis pigmentosa
por: Li, Cheng, et al.
Publicado: (2023)

An optimized protocol for retina single-cell RNA sequencing
por: Fadl, Benjamin R., et al.
Publicado: (2020)

Low Immunogenicity and Immunosuppressive Properties of Human ESC- and iPSC-Derived Retinas
por: Yamasaki, Suguru, et al.
Publicado: (2021)

Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo
por: Berkowitz, Bruce A., et al.
Publicado: (2018)

Neuronal Migration and Lamination in the Vertebrate Retina
por: Amini, Rana, et al.
Publicado: (2018)

Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina
por: Rohowetz, Landon J., et al.
Publicado: (2018)

Rewiring the Regenerated Zebrafish Retina: Reemergence of Bipolar Neurons and Cone-Bipolar Circuitry Following an Inner Retinal Lesion
por: McGinn, Timothy E., et al.
Publicado: (2019)

Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina
por: Yu, Jindan, et al.
Publicado: (2003)

Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina
por: Miesfeld, Joel B., et al.
Publicado: (2018)

Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper
por: Swain, Prabodha, et al.
Publicado: (2007)

Ultrastructural Circuitry in Retinal Cell Transplants to Rat Retina
por: Zucker, Charles L., et al.
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_p74hn9kb2e0nhth5qul994b5sf