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TIMP-2 Fusion Protein with Human Serum Albumin Potentiates Anti-Angiogenesis-Mediated Inhibition of Tumor Growth by Suppressing MMP-2 Expression

TIMP-2 protein has been intensively studied as a promising anticancer candidate agent, but the in vivo mechanism underlying its anticancer effect has not been clearly elucidated by previous works. In this study, we investigated the mechanism underlying the anti-tumor effects of a TIMP-2 fusion prote...

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Detalles Bibliográficos
Autores principales: Lee, Mi-Sook, Jung, Jae-In, Kwon, Seung-Hae, Lee, Sang-Mok, Morita, Kyoji, Her, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335789/
https://www.ncbi.nlm.nih.gov/pubmed/22545131
http://dx.doi.org/10.1371/journal.pone.0035710