M. tuberculosis Sliding β-Clamp Does Not Interact Directly with the NAD(+) -Dependent DNA Ligase

The sliding β-clamp, an important component of the DNA replication and repair machinery, is drawing increasing attention as a therapeutic target. We report the crystal structure of the M. tuberculosis β-clamp (Mtbβ-clamp) to 3.0 Å resolution. The protein crystallized in the space group C222(1) with...

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Detalles Bibliográficos
Autores principales: Kukshal, Vandna, Khanam, Taran, Chopra, Deepti, Singh, Nidhi, Sanyal, Sabyasachi, Ramachandran, Ravishankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335792/
https://www.ncbi.nlm.nih.gov/pubmed/22545130
http://dx.doi.org/10.1371/journal.pone.0035702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335792/
https://www.ncbi.nlm.nih.gov/pubmed/22545130
http://dx.doi.org/10.1371/journal.pone.0035702

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