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M. tuberculosis Sliding β-Clamp Does Not Interact Directly with the NAD(+) -Dependent DNA Ligase
The sliding β-clamp, an important component of the DNA replication and repair machinery, is drawing increasing attention as a therapeutic target. We report the crystal structure of the M. tuberculosis β-clamp (Mtbβ-clamp) to 3.0 Å resolution. The protein crystallized in the space group C222(1) with...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335792/ https://www.ncbi.nlm.nih.gov/pubmed/22545130 http://dx.doi.org/10.1371/journal.pone.0035702 |