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MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells

BACKGROUND: Regulator of G-protein Signaling 4 (RGS4) plays an important role in regulating smooth muscle contraction, cardiac development, neural plasticity and psychiatric disorder. However, the underlying regulatory mechanisms remain elusive. Our recent studies have shown that upregulation of Rgs...

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Detalles Bibliográficos
Autores principales: Zhang, Yonggang, Li, Fang, Liu, Shu, Wang, Hong, Mahavadi, Sunila, Murthy, Karnam S., Khalili, Kamel, Hu, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335800/
https://www.ncbi.nlm.nih.gov/pubmed/22545125
http://dx.doi.org/10.1371/journal.pone.0035646