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Distinct Effector Memory CD4(+) T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis

Two billion people worldwide are estimated to be latently infected with Mycobacterium tuberculosis (Mtb) and are at risk for developing active tuberculosis since Mtb can reactivate to cause TB disease in immune-compromised hosts. Individuals with latent Mtb infection (LTBI) and BCG-vaccinated indivi...

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Detalles Bibliográficos
Autores principales: Adekambi, Toidi, Ibegbu, Chris C., Kalokhe, Ameeta S., Yu, Tianwei, Ray, Susan M., Rengarajan, Jyothi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335801/
https://www.ncbi.nlm.nih.gov/pubmed/22545156
http://dx.doi.org/10.1371/journal.pone.0036046