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The EYA Tyrosine Phosphatase Activity Is Pro-Angiogenic and Is Inhibited by Benzbromarone

Eyes Absents (EYA) are multifunctional proteins best known for their role in organogenesis. There is accumulating evidence that overexpression of EYAs in breast and ovarian cancers, and in malignant peripheral nerve sheath tumors, correlates with tumor growth and increased metastasis. The EYA protei...

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Detalles Bibliográficos
Autores principales: Tadjuidje, Emmanuel, Wang, Tim Sen, Pandey, Ram Naresh, Sumanas, Saulius, Lang, Richard A., Hegde, Rashmi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335822/
https://www.ncbi.nlm.nih.gov/pubmed/22545090
http://dx.doi.org/10.1371/journal.pone.0034806