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APC/C-Mediated Degradation of dsRNA-Binding Protein 4 (DRB4) Involved in RNA Silencing

BACKGROUND: Selective protein degradation via the ubiquitin-26S proteasome is a major mechanism underlying DNA replication and cell division in all Eukaryotes. In particular, the APC/C (Anaphase Promoting Complex or Cyclosome) is a master ubiquitin protein ligase (E3) that targets regulatory protein...

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Detalles Bibliográficos
Autores principales: Marrocco, Katia, Criqui, Marie-Claire, Zervudacki, Jérôme, Schott, Gregory, Eisler, Herfried, Parnet, Aude, Dunoyer, Patrice, Genschik, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335838/
https://www.ncbi.nlm.nih.gov/pubmed/22545099
http://dx.doi.org/10.1371/journal.pone.0035173