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RAB-5 Controls the Cortical Organization and Dynamics of PAR Proteins to Maintain C. elegans Early Embryonic Polarity

In all organisms, cell polarity is fundamental for most aspects of cell physiology. In many species and cell types, it is controlled by the evolutionarily conserved PAR-3, PAR-6 and aPKC proteins, which are asymmetrically localized at the cell cortex where they define specific domains. While PAR pro...

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Detalles Bibliográficos
Autores principales: Hyenne, Vincent, Tremblay-Boudreault, Thierry, Velmurugan, Ramraj, Grant, Barth D., Loerke, Dinah, Labbé, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335856/
https://www.ncbi.nlm.nih.gov/pubmed/22545101
http://dx.doi.org/10.1371/journal.pone.0035286