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Heme Oxygenase Isoforms Differ in Their Subcellular Trafficking during Hypoxia and Are Differentially Modulated by Cytochrome P450 Reductase

Heme oxygenase (HO) degrades heme in concert with NADPH cytochrome P450 reductase (CPR) which donates electrons to the reaction. Earlier studies reveal the importance of the hydrophobic carboxy-terminus of HO-1 for anchorage to the endoplasmic reticulum (ER) which facilitates the interaction with CP...

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Detalles Bibliográficos
Autores principales: Linnenbaum, Monika, Busker, Mareike, Kraehling, Jan R., Behrends, Soenke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335857/
https://www.ncbi.nlm.nih.gov/pubmed/22545110
http://dx.doi.org/10.1371/journal.pone.0035483