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Downregulation of Integrin β4 Decreases the Ability of Airway Epithelial Cells to Present Antigens
Airway epithelial cells have been demonstrated to be accessory antigen presentation cells (APC) capable of activating T cells and may play an important role in the development of allergic airway inflammation of asthma. In asthmatic airways, loss of expression of the adhesion molecule integrin β4 (IT...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335869/ https://www.ncbi.nlm.nih.gov/pubmed/22545078 http://dx.doi.org/10.1371/journal.pone.0032060 |