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Downregulation of Integrin β4 Decreases the Ability of Airway Epithelial Cells to Present Antigens

Airway epithelial cells have been demonstrated to be accessory antigen presentation cells (APC) capable of activating T cells and may play an important role in the development of allergic airway inflammation of asthma. In asthmatic airways, loss of expression of the adhesion molecule integrin β4 (IT...

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Detalles Bibliográficos
Autores principales: Liu, Chi, Qin, Xiaoqun, Liu, Huijun, Xiang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335869/
https://www.ncbi.nlm.nih.gov/pubmed/22545078
http://dx.doi.org/10.1371/journal.pone.0032060