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Zinc Sensing Receptor Signaling, Mediated by GPR39, Reduces Butyrate-Induced Cell Death in HT29 Colonocytes via Upregulation of Clusterin

Zinc enhances epithelial proliferation, protects the digestive epithelial layer and has profound antiulcerative and antidiarrheal roles in the colon. Despite the clinical significance of this ion, the mechanisms linking zinc to these cellular processes are poorly understood. We have previously ident...

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Detalles Bibliográficos
Autores principales: Cohen, Limor, Azriel-Tamir, Hagit, Arotsker, Natan, Sekler, Israel, Hershfinkel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335870/
https://www.ncbi.nlm.nih.gov/pubmed/22545109
http://dx.doi.org/10.1371/journal.pone.0035482